Klinefelter’s Syndrome – Do You Have an Awkward Son or Grandson?

There are those who have never been diagnosed with this condition and even in our advancing years it would be great to be able to treat Klinefelter’s if you are a sufferer.

For those of us who aren’t suffering then this information may be of use to your children or grandchildren. If you think that one of your male relatives could have a problem you might want to refer them to this page.

Keep reading to see if you can help your boys and grandsons.

Back to Klinefelter’s Syndrome

This is a genetic abnormality that affects only males. It’s named after the American physician, Harry Klinefelter, and is a disorder that affects close to 1 in 1000 men. This rate of occurance makes Klinefelter’s Syndrome a rather common genetic abnormality.

The sex of a human being is basically determined by their chromosomes. In males there are one X and one Y chromosome (XY), and women there are two X chromosomes (XX). In the case of men with Klinefelter’s Syndrome there is an extra X chromosome (XXY) in their genetic material.

There is no specific cause for the occurrence of Klinefelter’s syndrome that we are aware of but we do know that women who have boys after they have reached an age of 35 have a great chance of giving birth to boys who suffer from Klinefelter’s.

The most obvious sign of Klinefelter’s is infertility and it is, most often, this symptom that makes men approach a physician that then diagnoses the condition. At times slow or untypical development during adolescence can also lead to a visit to a doctor that may diagnose the condition.

The reason suffers are often infertile and cannot father children is that their bodies produce little or no sperm and this is because Klinefelter’s retards the growth of their testicles and hence, produce none or very low volumes of testosterone. (ref)

Symptoms of Klinefelter’s

Possible At Birth Symptoms

Klinefelter's Syndrome Graphic

The condition is rarely diagnosed at birth but there are a number of possible tell-tale signs that are often overlooked:

  • small penis for a newborn and
  • Hypospadias (the urethera is located on the underside of the penis instead of the tip).

Early Childhood Symptoms

  • delayed walking or talking,
  • a small penis will be a permanent symptom throughout life
  • reduced muscle strength and tone,
  • sleep apnoea,
  • chronic constipation,
  • tiredness and fatique,
  • learning difficulties,
  • poor motor development and coordination which can lead to shyness and an avoidance of body contact sports and
  • trouble concentrating in class.

Early Adolesent Symptoms

  • reduced muscle mass,
  • small firm testicles (hypogonadism),
  • almond shaped eyes,
  • a single crease in the palm of the hand (simian crease),
  • sexual function issues,
  • depression, sadness and lowered moods,
  • delayed puberty,
  • poor concentration,
  • weight gain around the stomach,
  • tiredness and fatigue,
  • taller than average,
  • clumsy
  • difficulty with speaking, writing, or understanding and processing speech which can lead to behavioural problems,
  • non-normal body proportions (long legs and short trunks),
  • reduced body, facial and underarm hair, and
  • enlarged breast tissue (gynecomastia) (ref)

Note: The effects of Klinefelter syndrome vary, and not everyone with it develops all the  symptoms.

Possible Complication Associated with Klinefelter’s

Men with Klinefelter’s have higher risks associated with developing any of the following medical conditions:

  • Anaemia
  • Breast cancer
  • Diabetes mellitus
  • High cholesterol
  • Infertility
  • Leukaemia
  • Lung disease
  • Non-Hodgkin’s lymphoma
  • Osteoporosis
  • Sleep apnoea
  • Testicular cancerThyroid disease
  • Tooth decay
  • Varicose veins.

How a Diagnosis is Made

Diagnosed for Klinefelter’s syndrome is performed by:

  • blood tests – check testosterone levels,
  • genetic tests – to confirm existance or lack of an extra X chromosome,
  • observation – checks testicles to find out their size and hardness and
  • semen samples – to measure the proportion of semen.

How To Treat Klinefelter’s

One of the first treatment recomended to sufferers is to start a program of Testosterone Replacement therapy as it treats a number of the most obvious socially exclusionary and obvious symptoms:

  • reduced muscle strength and tone,
  • tiredness and fatique,
  • reduced muscle mass (not the same as reduced mass and tone),
  • depression, sadness and lowered moods,
  • weight gain around the stomach,
  • reduced body, facial and underarm hair, and
  • enlarged breast tissue (gynecomastia).

If you know you have Klinefelter’s then you might be interested in our Bioidentical Testosterone cream. Each bottle contains 200 daily doses each of 60mgs of testosterone for a total cost of $197.00

If you’re interested please check out or product offering here.

Applied to the scrotum (or any other thin skin – inner thight, or inner arm) it will treat the symptoms listed above.

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